ʻO ka piko pipette haʻahaʻa he liʻiliʻi, maʻalahi, a pono i ka ʻepekema. He mana ia i ka noiʻi ʻana i nā lāʻau lapaʻau hou, nā maʻi maʻi Covid-19 a me kēlā me kēia hoʻāʻo koko.
Akā i kēia manawa, ua hoʻokumu ʻia kahi ʻano o ka haunaele i ka pipette tip ma muli o ka pau ʻana o ka mana, ke ahi a me nā koi e pili ana i ka maʻi maʻi i hana i kahi hemahema o ka honua e hoʻoweliweli i nā kihi āpau o ke kaiāulu ʻepekema.
ʻO ka hemahema o nā ʻōlelo aʻoaʻo pipette ua hoʻopilikia i kahi papahana holoʻokoʻa no ka nānā ʻana i nā keiki hānau hou no nā maʻi hiki ke make, e like me ka hiki ʻole ke ʻeli i ke kō i ka waiū umauma. ka hoʻomua i kekahi mau hoʻokolohua ma mua o nā mea ʻē aʻe.
I kēia manawa, ʻaʻohe hōʻailona e pau koke ka hemahema - inā ʻoi aku ka maikaʻi o nā mea, pono paha ka poʻe ʻepekema e hoʻomaka e lohi i nā hoʻokolohua a haʻalele paha i kekahi o kā lākou hana.
"He mea lapuwale ka manaʻo o ka hiki ke hana ʻepekema me ka ʻole o lākou," wahi a Gabrielle Bostwick, ka luna hoʻokolohua ma Octant Bio, kahi hoʻomaka ʻana o ka biology synthetic ma Kaleponi.
ʻO ka poʻe ʻepekema āpau e huhū nei i ka hemahema, ʻo nā mea noiʻi i hana ʻia me ka nānā ʻana i nā pēpē ʻo ia ka mea i hoʻonohonoho ʻia a ʻōlelo ʻole.
ʻO nā keʻena olakino olakino e nānā i nā pēpē no ka nui o nā maʻi genetic i loko o nā hola o ka hānau ʻana. ʻO kekahi, e like me ka phenylketonuria a me MCAD deficiency, koi i nā kauka e hoʻololi koke i ke ʻano o kā lākou mālama ʻana i kā lākou pēpē. ke kaʻina hana i alakaʻi i kekahi mau keiki make.
Pono ka nānā ʻana i kēlā me kēia keiki ma kahi o 30 a 40 mau ʻōlelo aʻoaʻo pipette e hoʻopau ai i ka nui o nā hoʻokolohua diagnostic, a hānau ʻia nā tausani keiki ma ʻAmelika i kēlā me kēia lā.
Ma hope o Pepeluali, ua hoʻomaopopo nā labs ʻaʻole i loaʻa iā lākou nā lako e pono ai. Ua koi ʻo ia i ke aupuni pekelala, me ka Hale Paʻa, no nā mahina e hoʻomaka i ka pono o nā ʻōlelo aʻoaʻo pipette no ka papahana screening hou. nā ala e hoʻonui ai i ka loaʻa ʻana o ka tip.
I kekahi mau ʻāina, ʻo ka hemahema o ka plastik "aneane i alakaʻi i ka pani ʻana i kekahi mau papahana screening hou," ʻo Susan Tanksley, ka luna mahele o ka Texas Department of Health's Laboratory Services Division, i haʻi aku i kahi hālāwai o ke Kōmike Kūkākūkā Federal ma Newborn Screening i Pepeluali.i ʻōlelo ai.(ʻAʻole i pane aku ʻo Tankskey a me ke keʻena olakino o ka mokuʻāina i nā noi no ka ʻōlelo.)
Ua ʻōlelo ʻo Scott Shone, ka luna o ka North Carolina Public Health Laboratory, ua loaʻa i kekahi mau mokuʻāina he mau ʻōlelo aʻoaʻo me ka lā hoʻokahi wale nō i koe, me ka waiho ʻana iā lākou me ke koho ʻole e noi aku i ke kākoʻo mai nā labs ʻē aʻe. e ʻōlelo, 'Ke pau nei kaʻu kālā i ka lā ʻapōpō, hiki iā ʻoe ke loaʻa iaʻu i kekahi mea i ka pō?'No ka mea, ua ʻōlelo ka mea hoʻolako e hele mai ana, akā ʻaʻole wau i ʻike i kēlā.'”
"E manaʻoʻiʻo i ka ʻōlelo ʻana o kēlā mea hoʻolako, 'ʻEkolu mau lā ma mua o kou pau ʻana, e hāʻawi mākou iā ʻoe i ka lako o kekahi mahina' - ʻo ia ka hopohopo," wahi āna.
Ua huli ka nui o nā labs i nā mea ʻokoʻa i ka hoʻopunipuni jury. Hoʻomaʻemaʻe ʻia kekahi a hoʻohana hou ʻia, e hoʻonui ana i ka pilikia o ka hoʻomake ʻana.
I kēia manawa, ua lawa kēia mau hoʻonā.
Ma waho aʻe o nā laboratories screening newborns, ʻo nā hui biotech e hana ana i nā lāʻau lapaʻau hou a me nā hale hana o ke kulanui e hana ana i ka noiʻi kumu ke manaʻo nei i ka pinch.
Wahi a nā kānaka ʻepekema ma PRA Health Sciences, kahi hui noiʻi ʻaelike e hana ana i nā hoʻokolohua lapaʻau o ka maʻi hepa B a me kekahi mau moho lāʻau lapaʻau Bristol Myers Squibb, he mea hoʻoweliweli mau ka hoʻopau ʻana - ʻoiai ʻaʻole lākou i hoʻopaneʻe mua i nā heluhelu.
"I kekahi manawa, lilo ia i lālani o nā ʻōlelo aʻoaʻo ma ka papa hope, a ua like mākou me 'oh my gosh'" wahi a Jason Neat, ka luna hoʻokele o nā lawelawe bioanalytical ma PRA Health ma Kansas.
ʻO Kathleen McGinness, ke poʻo o ka biology RNA ma Arrakis Therapeutics, kahi hui e hana ana i nā lāʻau lapaʻau no ka maʻi kanesa, nā maʻi neurological a me nā maʻi laha ʻole, ua hana ʻo ia i kahi ala Slack i hoʻolaʻa ʻia e kōkua i kāna mau hoa e kaʻana like i ka ʻike.
"Ua ʻike mākou ʻaʻole ia he koʻikoʻi," i ʻōlelo ai ʻo ia no ke kahawai #tipsfortips.
ʻO ka hapa nui o nā hui biotech STAT i ʻōlelo ai e hana ana lākou i nā hana e pale ai i nā pipette palena ʻole a hiki i kēia manawa ʻaʻole i pau i ka hana.
No ka laʻana, koho nui nā kānaka ʻepekema ma Octant i ka hoʻohana ʻana i nā ʻōlelo aʻoaʻo pipette kānana. ʻO kēia mau ʻōlelo aʻoaʻo - he mea paʻakikī loa ke hele mai i kēia mau lā - hāʻawi i kahi papa o ka pale no nā laʻana mai nā mea haumia o waho, akā ʻaʻole hiki ke hoʻopaʻa ʻia a hoʻohana hou ʻia. .No laila, hoʻolalelale lākou iā lākou no nā hana i maʻalahi paha.
"Inā ʻaʻole ʻoe e noʻonoʻo i ka mea āu e hoʻohana ai, hiki iā ʻoe ke holo maʻalahi," wahi a Danielle de Jong, ka luna hoʻokolohua ma ka Whitney Laboratory ma ke Kulanui o Florida, kahi ʻāpana o ka lab e aʻo ana i ke ʻano o ke kumu. hana nā cell i nā holoholona liʻiliʻi liʻiliʻi e pili ana i ka jellyfish.Ke hana nei, hiki i kēia mau holoholona ke hana hou i nā ʻāpana o lākou iho.
ʻO ka poʻe ʻepekema ma Whitney Lab i kekahi manawa e hoʻopakele i ko lākou mau hoalauna ke hiki ʻole mai nā kauoha hoʻolako i ka manawa.
"He 21 makahiki au i loko o ka lab," i ʻōlelo ai ʻo ia.mau loa."
ʻO ka pahū koke ʻana o nā hoʻokolohua Covid-19 i ka makahiki i hala - ua hilinaʻi kēlā me kēia mea i nā ʻōlelo aʻoaʻo pipette - he hana maoli nō.
ʻO ka pau ʻana o ka mana o ka mokuʻāina ʻo Texas i make ma mua o 100 mau kānaka a ua hoʻopau i kahi loulou kī i loko o ke kaulahao hoʻolako pipette paʻakikī. ʻōlelo aʻoaʻo paipu.
ʻO Exxon's Houston-area mea kanu ʻo ia ka lua o ka nui o ka polypropylene mea hana ma 2020, e like me ka hōʻike o Malaki;ʻO kāna mea kanu Singapore wale nō i hana hou aku. ʻElua o nā mea kanu polyethylene nui loa ʻekolu o ExxonMobil aia ma Texas.
"Ma hope o nā ʻino hoʻoilo i Pepeluali i kēia makahiki, ua manaʻo ʻia ua ʻoi aku ma mua o 85% o ka mana polypropylene i ʻAmelika Hui Pū ʻIa i hoʻopilikia ʻia e nā pilikia like ʻole e like me ka haki ʻana o ka pipeline, ka pau ʻana o ka mana, a me ka pau ʻana o ka mana ma nā mea kanu hana.He mea waiwai nui e pono ai e hoʻomaka hou i ka hana ʻana, "wahi a kekahi mea hana polypropylene.Ua ʻōlelo ʻia kahi ʻōlelo no ka hui aila a me ka hui kinoea o Houston.
Akā, ua hoʻemi ʻia nā kaulahao hoʻolako mai ke kauwela i hala - ma mua o ka hoʻoilo hohonu ʻana i Pepeluali. .
Ua hoʻopau pū kekahi ahi mea kanu i ka hāʻawi ʻana i ka 80 pakeneka o nā ipu o ka ʻāina o nā ʻōlelo aʻoaʻo pipette i hoʻohana ʻia a me nā mea koi ʻē aʻe, e like me kahi palapala i kau ʻia ma ka pūnaewele o ke Kulanui o Pittsburgh.
I Iulai, ua hoʻomaka ʻo US Customs and Border Protection i ka pale ʻana i nā huahana mai kahi mea hana mīkina lima nui i manaʻo ʻia he hana koi.
"ʻO ka mea a mākou e ʻike maoli nei, ʻo ka ʻoihana pili i ka plastics - polypropylene ma ke ʻano nui - ʻaʻole i kūʻai ʻia a i ʻole koi nui ʻia," wahi a PRA Health Sciences 'Neat.
He kiʻekiʻe loa ka makemake a ua piʻi aʻe nā kumukūʻai no kekahi mau lako liʻiliʻi, wahi a Tiffany Harmon, ka luna hoʻomalu kūʻai ma PRA Health Sciences 'bioanalytical laboratory ma Kansas.
Ke uku nei ka hui i 300% hou aku no nā mīkina lima ma o kāna mau mea hoʻolako maʻamau. Loaʻa i kēia manawa nā kauoha pipette tip a PRA i kēia manawa no kahi uku hou. ʻO kahi mea hana o nā ʻōlelo aʻoaʻo pipette, i hoʻolaha ʻia i ka mahina i hala he uku hou o 4.75 pakeneka, ua haʻi aku i kāna mea kūʻai aku he pono ka neʻe. no ka mea, ua aneane pālua ke kumu kūʻai o nā mea palaka.
ʻO ka hoʻohui ʻana i ka maopopo ʻole o ka poʻe ʻepekema lab ʻo ia ke kaʻina hana e hoʻoholo ai nā mea hoʻolaha i nā kauoha e hoʻopiha mua ʻia - ʻōlelo ka poʻe ʻepekema liʻiliʻi ua maopopo lākou i ke ʻano o kēia hana.
"Ua noi ke kaiāulu lab mai ka hoʻomaka ʻana e kōkua iā mākou e hoʻomaopopo i ke ʻano o kēia mau hoʻoholo ʻana," wahi a Shone, ka mea i kapa i nā mea kūʻai aku e hoʻohana ai e hoʻoholo i nā ʻāpana "black-box magic."
Ua hoʻopili aku ʻo STAT ma mua o ka ʻumi mau ʻoihana e hana a kūʻai aku i nā ʻōlelo aʻoaʻo pipette, me Corning, Eppendorf, Fisher Scientific, VWR a me Rainin. ʻElua wale nō pane.
Ua hōʻole ʻo Corning i ka ʻōlelo ʻana, me ka ʻōlelo ʻana i nā kuʻikahi ponoʻī me nā mea kūʻai aku.
"ʻO ka noi no nā huahana pili Covid-19, ʻo ia hoʻi ʻo MilliporeSigma, ʻaʻole i loaʻa ma mua o ka ʻoihana ʻepekema ola mai ka hoʻomaka ʻana o ka maʻi maʻi maʻi," i ʻōlelo ʻia e kahi ʻōlelo no ka ʻoihana hāʻawi ʻepekema nui i STAT i kahi leka uila. "Ke hana nei mākou i 24. /7 no ka hoʻokō ʻana i ka nui o ka noi no kēia mau huahana a me nā mea i hoʻohana ʻia no ka ʻike ʻepekema.
ʻOiai ka hoʻāʻo ʻana e hoʻoikaika i nā kaulahao lako, ʻaʻole maopopo ka lōʻihi o ka pau ʻana o nā hemahema.
Ua loaʻa iā Corning he $15 miliona mai ka US Department of Defense e hana i 684 miliona mau ʻōlelo aʻoaʻo pipette i kēlā me kēia makahiki ma kāna hale ma Durham, North Carolina. Ke hoʻohana nei ʻo Tecan i ka $32 miliona o CARES Act no ke kūkulu ʻana i kahi hale hana hou.
Akā ʻaʻole ia e hoʻonā i ka pilikia inā ʻoi aku ka haʻahaʻa o ka hana plastik ma mua o ka mea i manaʻo ʻia.
A hiki i kēlā manawa, ke mākaukau nei nā luna lab a me nā ʻepekema no ka hemahema o nā pipettes a me nā mea ʻē aʻe.
"Ua hoʻomaka mākou i kēia maʻi maʻi me ka ʻole o ka swabs a me ka ʻole o ka media.A laila ua nele mākou i nā reagents.A laila ua nele mākou i nā plastics.A laila ua nele mākou i nā reagents, "wahi a North Carolina's Shone." Ua like ia me Groundhog Day.
Hoʻohou: Ma hope o ka paʻi ʻia ʻana o kēia moʻolelo, ua wehewehe ʻo MilliporeSigma e hoʻohana ana ia i kahi ʻōnaehana hele mua, lawelawe mua e hāʻawi i nā ʻōlelo aʻoaʻo pipette, ma mua o ka ʻōnaehana ʻehā i wehewehe mua ʻia.
ʻOhi a kālailai ʻo Kate i nā palapala, ʻikepili a me nā ʻike ʻē aʻe no ka biotech, ʻenehana olakino, ʻepekema a me nā moʻolelo politika.
ʻO Kate, he ʻatikala maikaʻi kēia e hoʻomaopopo i ka poʻe āpau e pili ana i kēia mau pilikia nui o ka hoʻolako ʻana i ka ʻoihana. Ua hana koʻikoʻi ʻo ia i ka hoʻoponopono ʻana i ka hemahema o nā ʻōlelo aʻoaʻo pipette i loko o ka COVID a me nā mākeke ʻoihana non-COVID i hana nui i ka makahiki 2020. Ua loaʻa i ka 90% ka emi ʻana o nā koi pipette tip a me ka hōʻemi nui ʻana i ke kumukūʻai a me ka ʻōpala plastic. Aia mākou ma ʻaneʻi e kākoʻo i ka ʻoihana a hōʻike i nā labs āpau e loaʻa iā Grenova kahi hopena hoʻomau i ke kaulahao hāʻawi pipette tip. ʻO Ali Safavi Pelekikena a me Luna Nui ʻo Grenova, Inc.
Auwe. Hana paha kēlā me kēia kemika mai loko mai o nā paipu aniani (e ho'opa'a i ka paipu ma kēlā me kēia wēlau, e wela i ka waena ma luna o ke kapuahi bunson, e huki mālie… e puka i waho o ke kapuahi… e ki'i koke i 2 paipu). e hōʻike ana i koʻu mau makahiki…
Ka manawa hoʻouna: Mei-24-2022