nsonga yochepetsetsa ya pipette ndi yaying'ono, yotsika mtengo, komanso yofunikira kwa sayansi. Imapatsa mphamvu kafukufuku wamankhwala atsopano, matenda a Covid-19 ndi kuyezetsa magazi kulikonse.
Koma tsopano, kusokonekera kwanthawi yayitali pamakina amtundu wa pipette chifukwa cha kuzimitsidwa kwa magetsi, moto ndi zofuna zokhudzana ndi mliri zadzetsa kusowa kwapadziko lonse komwe kukuwopseza pafupifupi mbali zonse za asayansi.
Kuperewera kwa malangizo a pipette kwayika pachiwopsezo pulogalamu yapadziko lonse yowunikira ana obadwa kumene kuti ali ndi matenda oopsa, monga kulephera kugaya shuga mu mkaka wa m'mawere. Izi zikuwopseza mayunivesite a stem cell genetics experiments.Zikukakamizanso makampani opanga sayansi yaukadaulo omwe akugwira ntchito yopanga mankhwala atsopano oti aganizire. kuika patsogolo zoyeserera zina kuposa zina.
Pakalipano, palibe chizindikiro chakuti kuchepa kutha posachedwa - ngati zinthu zikuipiraipira, asayansi angafunike kuyamba kuchedwetsa kuyesa kapena kusiya ntchito zawo zina.
"Lingaliro lotha kuchita sayansi popanda iwo ndi lodabwitsa," atero a Gabrielle Bostwick, woyang'anira labotale ku Octant Bio, woyambitsa biology yochokera ku California.
Mwa asayansi onse omwe akhumudwa chifukwa cha kuchepaku, ofufuza omwe adapatsidwa ntchito yowunika makanda ndi omwe ali okonzekera bwino komanso olankhula mosapita m'mbali.
Ma labotale a zaumoyo a anthu amawunika makanda chifukwa cha matenda ochuluka a majini pasanathe maola angapo atangobadwa. Ena, monga phenylketonuria ndi vuto la MCAD, amafuna kuti madokotala asinthe mwamsanga mmene amasamalirira ana awo. Malinga ndi kafukufuku wina wa mu 2013, ngakhale kuchedwa kuwunika kachitidweko kanadzetsa imfa zina za makanda.
Kuwunika kwa mwana aliyense kumafuna nsonga za 30 mpaka 40 kuti amalize mayeso ambiri, ndipo ana masauzande ambiri amabadwa ku United States tsiku lililonse.
Kubwerera mu February, ma laboratories adawonekeratu kuti alibe zinthu zomwe amafunikira.Ma laboratories m'mayiko 14 ali ndi malangizo ochepera mwezi umodzi a pipette omwe atsala, malinga ndi Association for Public Health Laboratories.Gululi likudandaula kwambiri kuti wakhala akukakamiza boma la federal, kuphatikizapo White House, kwa miyezi yambiri kuti liyike patsogolo kufunikira kwa malangizo a pipette kwa pulogalamu yowunikira ana obadwa kumene.Pakali pano, palibe chomwe chasintha, gululi linati. njira zowonjezera kupezeka kwa nsonga.
M’madera ena, kusowa kwa pulasitiki “kunachititsa kuti mapologalamu oyeza obadwa kumene atsekedwe,” Susan Tanksley, woyang’anira gawo la Dipatimenti ya Zaumoyo ku Texas Department of Health’s Laboratory Services Division, anauza msonkhano wa Federal Advisory Committee on Newborn Screening mu February.adatero.(Tankskey ndi dipatimenti ya zaumoyo m'boma sanayankhe zopempha kuti apereke ndemanga.)
Scott Shone, mkulu wa North Carolina Public Health Laboratory, adati mayiko ena adalandira upangiri patangotsala tsiku limodzi, kuwasiya alibe chochita koma kupempha thandizo kuchokera ku ma lab ena. kunena kuti, 'Ndalama zikundithera mawa, mungandipezerepo kanthu usikuuno?'Chifukwa wogulitsa anati ikubwera, koma sindinadziwe zimenezo.’”
"Khulupirirani kuti wogulitsa akanena kuti, 'Masiku atatu musanathe, tidzakupatsani mwezi wina' - ndiye nkhawa," adatero.
Ma lab ambiri atembenukira ku njira zina zopangira ma jury manipulation.Ena amatsukidwa ndikugwiritsidwanso ntchito, kuonjezera chiopsezo cha cross-contamination.Ena akupanga zowunikira posachedwapa m'magulu, zomwe zingawonjezere nthawi kuti zipereke zotsatira.
Pakadali pano, mayankho awa ndi okwanira. "Sitili mumkhalidwe womwe wakhanda amawopsezedwa nthawi yomweyo," Shone adawonjezera.
Kuphatikiza pa ma laboratories omwe amawunika ana obadwa kumene, makampani opanga sayansi yasayansi omwe amagwira ntchito pazamankhwala atsopano ndi ma laboratories akuyunivesite omwe amagwira ntchito pa kafukufuku wofunikira akumva chisoni.
Asayansi ku PRA Health Sciences, bungwe lofufuza za mgwirizano lomwe likugwira ntchito yoyesa matenda a hepatitis B ndi anthu angapo omwe akufuna kugwiritsa ntchito mankhwala a Bristol Myers Squibb, akuti kuchepa kwa chakudya ndikuwopseza kosalekeza - ngakhale sanachedwe kuwerenga.
"Nthawi zina, zimasandulika mndandanda wa malangizo pa alumali lakumbuyo, ndipo timakhala ngati 'oh my gosh,'" anatero Jason Neat, mkulu wa ntchito za bioanalytical ku PRA Health ku Kansas.
Kathleen McGinness, mkulu wa RNA biology ku Arrakis Therapeutics, kampani yomwe ikugwira ntchito zochizira khansa, matenda a ubongo ndi matenda osowa, adapanga njira yodzipatulira ya Slack kuti athandize anzake kugawana zambiri.Solution kuteteza nsonga za pipette.
"Tinazindikira kuti sizinali zovuta," adatero za njira ya #tipsfortips." Anthu ambiri m'gululi anali kufunafuna mayankho mwachangu, koma tinalibe malo oti tigawireko.
Makampani ambiri a biotech STAT adalankhula nawo adati akutenga njira zoteteza ma pipette ochepa ndipo mpaka pano sanasiye kugwira ntchito.
Mwachitsanzo, asayansi ku Octant ndi osankha kwambiri pankhani yogwiritsa ntchito malangizo a pipette osefedwa.Nsonga izi - zomwe zakhala zovuta kwambiri kubwera masiku ano - zimapereka chitetezo chowonjezera kwa zitsanzo kuchokera ku zowonongeka zakunja, koma sizingathetsedwe ndi kugwiritsidwanso ntchito. .Choncho, amawapangira ntchito zomwe zingakhale zovuta kwambiri.
"Ngati simusamala zomwe mumagwiritsa ntchito, mutha kutha," akutero a Danielle de Jong, manejala wa labotale ku Whitney Laboratory ku Yunivesite ya Florida, komwe ali gawo la labu lomwe limaphunzira momwe zimayambira. maselo amagwira ntchito mu nyama zazing'ono zam'madzi zokhudzana ndi jellyfish.Pogwira ntchito, nyamazi zimatha kupanganso mbali zina zake.
Asayansi a ku Whitney Lab nthawi zina amapereka ndalama kwa anansi awo akalamula kuti asafike nthawi yake.
“Ndakhala m’labu kwa zaka 21,” iye anatero.” Sindinakhalepo ndi vuto la chain chain monga chonchi.Nthawi zonse.”
Kuphulika kwadzidzidzi kwa mayeso a Covid-19 chaka chatha - chilichonse chomwe chimadalira maupangiri a pipette - ndithudi chinathandizira.
Kuzima kwa magetsi m'boma lonse ku Texas kudapha anthu opitilira 100 ndikusokoneza ulalo wofunikira mumayendedwe ovuta a pipette. malangizo a pipette.
Chomera cha Exxon's Houston chinali chachiwiri pamakampani opanga polypropylene mu 2020, malinga ndi lipoti la Marichi;Chomera chake cha ku Singapore chokha ndi chomwe chinatulutsa zambiri.Ziwiri mwazomera zitatu zazikulu kwambiri za polyethylene za ExxonMobil zimapezekanso ku Texas.
“Mphepo yamkuntho itatha mu February chaka chino, akuti oposa 85 peresenti ya mphamvu ya polypropylene ku United States yakhudzidwa kwambiri ndi mavuto osiyanasiyana monga kuphulika kwa mapaipi, kuzima kwa magetsi, ndi kuzimitsa kwa magetsi kumalo opangira zinthu.Zida zofunika kwambiri kuti muyambitsenso kupanga, "adatero wopanga wina wa polypropylene.Mneneri wa kampani yamafuta ndi gasi ku Houston Total adatero.
Koma maunyolo operekera akhala akupanikizika kuyambira chilimwe chatha - kuzizira kwambiri kusanachitike mu February. Kutsika-kuposa-wamba kwa zipangizo zopangira sizinthu zokhazo zomwe zimalepheretsa maunyolo operekera-komanso nsonga za pipette ndizo zida za labu zapulasitiki zokha zomwe sizikusowa. .
Moto wopangira mafakitale udasokonezanso kupezeka kwa 80 peresenti ya nkhokwe zapaipi zomwe zidagwiritsidwa ntchito m'dzikolo ndi zida zina zakuthwa, malinga ndi chikalata chomwe chidatumizidwa patsamba la University of Pittsburgh.
Mu Julayi, US Customs and Border Protection inayamba kutsekereza katundu kwa wopanga magolovesi wamkulu yemwe akuwaganizira kuti akugwira ntchito yokakamiza. (CBP idatulutsa zomwe idapeza mwezi watha.)
"Zomwe tikuwona ndizakuti bizinesi yokhudzana ndi mapulasitiki - makamaka polypropylene - mwina yatha kapena ikufunika kwambiri," adatero PRA Health Sciences 'Neat.
Kufuna ndikwambiri kotero kuti mitengo yazinthu zina zosoŵa yakwera, atero a Tiffany Harmon, woyang'anira zogula ku labotale ya PRA Health Sciences ku Kansas.
Kampaniyo tsopano ikulipira 300% yowonjezereka kwa magolovesi kudzera mwa ogulitsa ake omwe nthawi zonse.Malangizo a pipette a PRA tsopano akupezeka kuti apereke ndalama zowonjezera.Wopanga malangizo a pipette, omwe mwezi watha adalengeza kuti adzalandira 4.75 peresenti, adauza makasitomala ake kuti kusuntha kunali kofunikira. chifukwa mtengo wa zipangizo zamapulasitiki watsala pang'ono kuwirikiza kawiri.
Chowonjezera ku kukayika kwa asayansi a labotale ndi njira yomwe ogawa amazindikira kuti ndi maoda ati omwe ayambe kudzazidwa - asayansi ochepa amati amamvetsetsa bwino momwe izi zimagwirira ntchito.
"Mabungwe a labotale afunsa kuyambira pachiyambi kuti atithandize kumvetsetsa momwe zisankhozi zimapangidwira," atero a Shone, omwe amatcha ogulitsa ma formula omwe amagwiritsa ntchito kuti adziwe zomwe zagawika "zamatsenga amtundu wakuda."
STAT inalumikizana ndi makampani oposa khumi ndi awiri omwe amapanga kapena kugulitsa malangizo a pipette, kuphatikizapo Corning, Eppendorf, Fisher Scientific, VWR ndi Rainin. Pali mayankho awiri okha.
Corning anakana kuyankhapo, potchula mapangano ogwirizana ndi makasitomala.Panthawiyi, MilliporeSigma adanena kuti amapereka pipettes poyambira, choyamba.
"Kufunika kwa zinthu zokhudzana ndi Covid-19, kuphatikiza MilliporeSigma, sikunachitikepo m'makampani onse a sayansi ya moyo kuyambira pomwe mliriwu udayamba," wolankhulira kampani yayikulu yogawa zinthu zasayansi adauza STAT m'mawu omwe adatumizidwa ndi imelo. /7 kuti akwaniritse kufunikira kwa zinthu izi komanso zomwe zimagwiritsidwa ntchito potulukira sayansi. "
Ngakhale kuyesa kulimbikitsa maunyolo operekera, sizikudziwika kuti kuchepaku kudzakhala nthawi yayitali bwanji.
Corning adalandira $ 15 miliyoni kuchokera ku US Department of Defense kuti apange maupangiri owonjezera a 684 miliyoni pachaka pamalo ake ku Durham, North Carolina.Tecan akugwiritsanso ntchito ndalama zokwana $32 miliyoni za CARES Act kuti amange malo atsopano opangira zinthu.
Koma izi sizingathetse vutoli ngati kupanga pulasitiki kumakhalabe kochepa kuposa momwe amayembekezera. Mulimonsemo, palibe ntchito iliyonse yomwe ingathe kupanga nsonga za pipette pofika 2021.
Mpaka nthawi imeneyo, oyang'anira ma lab ndi asayansi akufunafuna kusowa kwa ma pipette ndi china chilichonse.
"Tidayambitsa mliriwu popanda ma swabs komanso opanda media.Ndiye tinali ndi kuchepa kwa reagents.Kenako tinasowa mapulasitiki.Kenako tinali ndi kuchepa kwa ma reagents, "adatero Shone waku North Carolina." Zili ngati Tsiku la Groundhog.
Zosintha: Nkhaniyi itasindikizidwa, MilliporeSigma adalongosola kuti imagwiritsa ntchito njira yoyamba, yoyamba yoperekedwa kuti ipereke malangizo a pipette, m'malo mwa dongosolo la magawo anayi omwe adalongosola poyamba.Nkhaniyi tsopano ikuwonetsa zosintha pa kampaniyo.
Kate amasonkhanitsa ndikusanthula zikalata, zidziwitso ndi zidziwitso zina za biotech, zaumoyo, sayansi ndi nkhani zandale.
Kate, iyi ndi nkhani yabwino yodziwitsa aliyense za zovuta zazikuluzikulu zomwe zikuchitika pamsika. Ndikufuna kugawana nanu kuti Grenova (www.grenovasolutions.com) yanyadira kupereka ma laboratories ndi mayankho otsimikizika komanso okhazikika komanso adachitapo kanthu pothana ndi kuchepa kwa maupangiri a pipette m'misika ya labotale ya COVID komanso yopanda COVID idachita gawo lofunikira mu 2020. zinapangitsa kuti pakhale kuchepa kwa 90% pa zofunikira za nsonga za pipette ndi kuchepetsa kwakukulu kwa mtengo ndi zinyalala za pulasitiki.Tili pano kuti tithandize makampaniwa ndikudziwitsa ma lab onse kuti Grenova ali ndi njira yokhazikika yopezera nsonga ya pipette. Ali Safavi Purezidenti ndi CEO Grenova, Inc.
Wow! Katswiri aliyense wamankhwala amawapanga kuchokera ku machubu agalasi (gwirani chubu kumapeto kulikonse, tenthetsani pakati pa choyatsira chowotcha, kokani pang'onopang'ono…tulukani muzowotchera…pezani ma pipette awiri mwachangu). kuwonetsa zaka zanga…
Nthawi yotumiza: May-24-2022