Incam yepipette ethobekileyo incinci, itshiphu, kwaye ibaluleke kakhulu kwisayensi.Inika amandla uphando kumayeza amatsha, uxilongo lwe-Covid-19, kunye nalo lonke uvavanyo lwegazi oluke lwenziwa.
Ikwanjalo, iqhelekile, ininzi-isazi sebhentshi esiqhelekileyo sinokubamba ezininzi mihla le.
Kodwa ngoku, uthotho lwekhefu elingenaxesha elibi ecaleni kwekhonkco lokubonelela ngepipette - ekhuthazwa kukucima ubumnyama, imililo, kunye nemfuno enxulumene nobhubhane - idale ukunqongophala kwehlabathi okusongela phantse zonke iimbombo zehlabathi.
Ukunqongophala kwetip ye-pipette sele ibeka emngciphekweni iinkqubo kwilizwe liphela ezivavanya iintsana ezisandula ukuzalwa kwiimeko ezinokuba yingozi, njengokungakwazi ukwetyisa iswekile kubisi lwebele.Yimvavanyo esongela idyunivesiti kwi-stem cell genetics.Kwaye kunyanzelisa iinkampani zebhayoloji ezisebenzela ukuphuhlisa amachiza amatsha ukuba zithathele ingqalelo ukubeka phambili imifuniselo ethile ngaphezu kwamanye.
Okwangoku, akukho mqondiso wokuba ukunqongophala kuya kuphela kungekudala-kwaye ukuba kuya kusiba mandundu, izazinzulu kusenokufuneka ziqale ukuhlehlisa iimvavanyo okanye zilahle iinxalenye zomsebenzi wazo.
Kuzo zonke izazinzulu ezingonwabanga kukunqongophala, abaphandi abanoxanduva lokuhlola iintsana ngabona bacwangcisiweyo kwaye bathetha ngokuphandle.
Iilebhu zoluntu zempilo zivavanya iintsana kwisithuba seeyure zokubeleka kuthotho lweemeko zofuzo.Abanye, njenge-phenylketonuria kunye nokusilela kwe-MCAD, bafuna ukuba oogqirha batshintshe ngokukhawuleza indlela abanyamekela ngayo umntwana.Kwanokulibaziseka nje kwinkqubo yokuhlola kukhokelele ekubhubheni kweentsana, ngokophando luka-2013.
Ukuhlolwa komntwana ngamnye kufuna amacebiso amalunga nama-30 ukuya kwangama-40 ukuze kugqitywe intaphane yovavanyo lokuxilonga, yaye amawakawaka abantwana azalwa suku ngalunye eUnited States.
Kwangoko ngoFebruwari, ezi lab zaziyenza icace into yokuba abanazo izinto abazidingayo.IiLebhu kumazwe ali-14 zineengcebiso ezingaphantsi kwenyanga ezishiyekileyo, ngokutsho koMbutho weeLebhu zoLuntu lwezeMpilo.Eli qela lalixhalabile kangangokuba, kangangeenyanga, licinezele urhulumente wesigqeba - kuquka neNdlu ye-White House - ukubeka phambili iimfuno zengcebiso ye-pipette yeenkqubo zokuhlola ezisanda kuzalwa.Ukuza kuthi ga ngoku, umbutho uthi, akukho nto itshintshileyo;i-White House yaxelela i-STAT ukuba urhulumente usebenza ngeendlela ezininzi zokwandisa ukufumaneka kweengcebiso.
Kwamanye amagunya, ukunqongophala kweeplastiki “kuphantse kubangele ukuba iinxalenye zenkqubo yokuhlolwa kweentsana ezisanda kuzalwa zivale,” utshilo uSusan Tanksley, umphathi wesebe kwicandelo leenkonzo zelabhoratri yesebe lezempilo laseTexas, ngexesha lentlanganiso kaFebruwari yekomiti yabacebisi malunga novavanyo olusanda kuzalwa. .(I-Tankskey kunye nesebe lezempilo likarhulumente abazange baphendule kwisicelo sokuphawula.)
Amanye amazwe afumana iibhetshi zeengcebiso kusele usuku nje olushiyekileyo, ebashiya benokhetho oluncinci ngaphandle kokucela ezinye iilebhu ukuba zigcinwe, ngokukaScott Shone, umlawuli welebhu yezempilo yoluntu yaseNorth Carolina.U-Shone uthe uve ngamagosa ezempilo kawonke-wonke efowuna “esithi, 'Ndiza kuphelelwa ngomso, ungandixelela into ethile?'Kuba umthengisi uthi iyeza, kodwa andazi.'
"Ukuthembela xa umthengisi esithi, 'Kwiintsuku ezintathu ngaphambi kokuba uphelelwe, siza kukufumana enye inyanga' - yinkxalabo," watsho.
Iilebhu ezininzi zijike kwiindlela ezizezinye ze-jury-rigged.Abanye bahlamba amacebiso baze baphinde bawasebenzise, oko kwandisa umngcipheko wokungcola.Abanye baqhuba uvavanyo olusanda kuzalwa kwiibhetshi, ezinokonyusa ixesha elithathayo ukuhambisa iziphumo.
Ukuza kuthi ga ngoku, ezi zisombululo zanele.“Asikho kwimeko apho kukho umngcipheko kwangoko kubantwana abasanda kuzalwa,” wongeze watsho uShone.
Ngaphaya kweelebhu ezihlola iintsana ezisanda kuzalwa, iinkampani zebhayoloji ezisebenza kunyango olutsha kunye neelebhu zaseyunivesithi ezenza uphando olusisiseko nazo ziyaziva zicudiswa.
Izazinzulu kwi-PRA Health Sciences, umbutho wophando lwekhontrakthi osebenza kulingo lwezonyango lwe-hepatitis B kunye neqela labagqatswa bamayeza eBristol Myers Squibb, bathi amayeza aphelayo sisisoyikiso esithe rhoqo - nangona bengekalibazisi ngokusesikweni naluphi na ufundo.
"Ngamanye amaxesha, ihla iye kwi-rack enye yeengcebiso ehleli kwi-shelf engasemva, kwaye sifana 'Owu Thixo wam,'" watsho uJason Neat, umlawuli olawulayo weenkonzo ze-bioanalytical kwilebhu ye-PRA Health eKansas.
Ukunqongophala kuye kwaba yinto eyoyikisayo ngokwaneleyo kwi-Arrakis Therapeutics, inkampani yaseWaltham, Mass. izisombululo zokugcina iingcebiso zepipette.
“Siye saqonda ukuba le ibingeyongxaki,” utshilo malunga netshaneli, #tipsfortips."Iqela elininzi lithathe amanyathelo angxamisekileyo malunga nezisombululo, kodwa besingenayo indawo esembindini yokwabelana ngaloo nto."
Uninzi lweenkampani zebhayoloji ekwenziwe udliwano-ndlebe nazo yi-STAT zathi zithatha amanyathelo okugcina iipipette ezilinganiselweyo kwaye, ukuza kuthi ga ngoku, akunyanzelekanga ukuba ziwumise umsebenzi.
Izazinzulu ze-Octant, umzekelo, zikhetha kakhulu ukusebenzisa iingcebiso zepipette ezihluziweyo.Ezi ngcebiso - ekunzima kakhulu ukuzifumana mva nje - zibonelela ngeesampulu umaleko owongezelelekileyo wokhuseleko kwizinto ezingcolisayo zangaphandle, kodwa azinakucocwa kwaye ziphinde zisetyenziswe.Ngoko ke babanikezela kwimisebenzi enokuba novakalelo olukhethekileyo.
“Ukuba awunikeli ngqalelo kwinto ephelayo, unokuphelelwa zizinto ngokulula,” utshilo uDanielle de Jong, umphathi walebhu kwiYunivesithi yaseFlorida yaseWhitney Laboratory;ilebhu asebenza kuyo kwizifundo zendlela iiseli ezisebenza ngayo kwizilwanyana zaselwandle ezincinci ezinxulumene nejellyfish ezinokuphinda zivelise iinxalenye zazo.
Izazinzulu kwi-Whitney Laboratory ziye, maxa wambi, bakhupha abamelwane babo xa imiyalelo yonikezelo ingafikanga ngexesha;U-de Jong uye wazibamba ejonge ezinye iishelufu zeelebhu ngazo naziphi na iingcebiso zepipette ezingasetyenziswanga, nje ukuba ilebhu yakhe ifuna ukuboleka ezinye.
“Ndineminyaka engama-21 ndisebenza elebhu,” utshilo.“Zange ndidibane nemiba yokuthengwa kwempahla efana nale.Nanini na.”
Akukho ngcaciso inye yokunqongophala.
Uqhushumbo ngequbuliso lovavanyo lwe-Covid-19 kulo nyaka uphelileyo - nganye ixhomekeke kwiingcebiso zepipette - ngokuqinisekileyo idlale indima.Kodwa iziphumo zeentlekele zendalo kunye nezinye iingozi ezothusayo eziqhubela phambili kwikhonkco lokubonelela nazo ziye zehla kwiibhentshi zaselabhoratri.
Ukucima kukagesi kwilizwe lonke eTexas, okubulale abantu abangaphezu kwe-100, kwaphule ikhonkco elibalulekileyo kwikhonkco lokubonelela ngepipette.Oko kucinywa kombane kunyanzelise i-ExxonMobil kunye nezinye iinkampani ukuba zivale okwethutyana izityalo kurhulumente - ezinye zazo zenza i-polypropylene resin, izinto eziluhlaza kwiingcebiso zepipette.
Ngokutsho komboniso kaMatshi, isityalo se-ExxonMobil saseHouston yayiyeyesibini kwinkampani enkulu yokuvelisa i-polypropylene ngo-2020;kuphela isityalo sayo saseSingapore senza okungakumbi.Ezibini zezityalo ezintathu ezinkulu ze-polyethylene ze-ExxonMobil nazo zazibekwe eTexas.(Ngo-Epreli ka-2020, i-ExxonMobil yaze yanyusa imveliso yepolypropylene kwizityalo ezibini ezise-US.)
"Emva kwesaqhwithi sasebusika ngoFebruwari kulo nyaka, kuqikelelwa ukuba ngaphezulu kwe-85% yomthamo wokuvelisa i-polypropylene e-US yachatshazelwa kakubi ngenxa yemicimbi eyahlukeneyo efana nemibhobho eyaphukileyo kwizityalo zemveliso kunye nokulahleka kombane kunye nombane. izinto ezikrwada ezibalulekileyo ezifunekayo ukuqalisa kwakhona imveliso, ”utshilo isithethi seTotal, enye inkampani ye-oyile negesi eseHouston evelisa i-polypropylene.
Kodwa amatyathanga obonelelo agxininisiwe ukusukela kwihlobo elidlulileyo - kwangaphambi kokuba kube ngumkhenkce onzulu kaFebruwari.Izixa-mali ezisezantsi kunesiqhelo zemathiriyeli ekrwada ayisiyiyo yodwa into ethe rhuthu amatyathanga onikezelo - kwaye iingcebiso ze-pipette ayikuphela kweqhekeza leplastiki esekwe kwilebhu ebinqongophele.
Umlilo weplanti yokuvelisa wakhupha i-80% yokunikezelwa kwelizwe kwiibhokisi zeengcebiso ezisetyenzisiweyo ze-pipette kunye nezinye izinto ezibukhali, ngokutsho koxwebhu olufakwe kwiwebhusayithi yeYunivesithi yasePittsburgh.
Kwaye ngoJulayi, i-US Customs kunye noKhuseleko lweBorder lwaqala ukuthintela iimveliso ezivela kumenzi omkhulu weglavu okrokrelwayo ngezenzo zokunyanzeliswa komsebenzi.(I-CBP ikhuphe iziphumo zophando lwayo kwinyanga ephelileyo.)
"Into esiyibonayo ngokwenene nantoni na kwicala leplastiki elinxulumene neshishini - i-polypropylene, ngokukodwa - mhlawumbi i-backorder, okanye ifunwa kakhulu," yatsho i-PRA Health Sciences 'Neat.
Imfuno iphezulu kakhulu kangangokuba ixabiso lezinto ezinqabileyo linyukile, ngokukaTiffany Harmon, umlawuli wokuthenga kwilebhu ye-PRA Health Sciences 'bioanalytics eKansas.
Inkampani ngoku ihlawula i-300% ngaphezulu kwiiglavu ngokusebenzisa umboneleli wayo wesiqhelo.Kwaye iiodolo zeengcebiso ze-PRA's pipette ngoku zinemali eyongezelelweyo efakiweyo.Omnye umenzi we-pipette tip, obhengeze intlawulo entsha ye-4.75% kwinyanga ephelileyo, uxelele abathengi bakhe ukuba oku kuyafuneka kuba ixabiso lezinto zeplastiki ekrwada liphantse laphindeka kabini.
Ukongeza kokungaqiniseki kwezazinzulu zaselabhoratri yinkqubo yabasasazi yokufumanisa ukuba zeziphi na iiodolo eziya kuzaliswa kuqala - ukusebenza apho izazinzulu ezimbalwa ziye zathi zaziyiqonda ngokupheleleyo.
“Uluntu lwaselebhu belibuza kwasekuqaleni ukuba lisincede siqonde ukuba zithathwa njani ezi zigqibo,” utshilo uShone, obhekisele kwiifomula zabathengisi zokumisela ulwabiwo “njengomlingo webhokisi emnyama.”
I-STAT yaqhagamshelana neenkampani ezingaphezu kweshumi elinesibini ezenza okanye ezithengisa iingcebiso ze-pipette, kuquka i-Corning, i-Eppendorf, i-Fisher Scientific, i-VWR, kunye ne-Rainin.Kwasabela nje ababini.
UCorning unqabile ukuphawula, ecaphula izivumelwano zobunini kunye nabathengi bakhe.I-MilliporeSigma, okwangoku, yathi inikezela ngeepipettes ngokuza kuqala, isiseko sokuqala.
Ukusukela oko kwaqhambuka lo bhubhani, ishishini lesayensi yobomi lilonke lifumene imfuno engazange ibonwe ngaphambili yeemveliso ezinxulumene ne-Covid-19, kubandakanya iMilliporeSigma, "isithethi senkampani enkulu yokuhambisa izinto zesayensi uxelele i-STAT kwingxelo ye-imeyile."Sisebenza ngama-24/7 ukuhlangabezana nale mfuno inyukileyo yezi mveliso kunye nezo zisetyenziselwa ukufunyanwa kwesayensi."
Ngaphandle kweenzame zokuqinisa ikhonkco lokubonelela, akucaci ukuba ukunqongophala kuya kuhlala ixesha elingakanani.
I-Corning ifumene i-15 yezigidi zeedola kwiSebe lezoKhuselo ukwenza i-684 yezigidi zeengcebiso ze-pipette ngonyaka kwiziko layo e-Durham, i-NC Tecan, nayo, yakha amaziko okuvelisa amatsha kunye ne-32 yezigidi zeedola kwi-CARES Act.
Kodwa loo nto ayizukulungisa ingxaki ukuba imveliso yeplastiki ihlala isezantsi kunokuba bekulindelwe.Kwaye akukho nanye kwezo projekthi ziya kuba nakho ukuvelisa iingcebiso ze-pipette ngaphambi kokuwa kwe-2021, kunjalo.
Kuze kube ngoko, abaphathi beelabhoratri kunye noososayensi bajongana nokunqongophala okungaphezulu kweepipettes kunye nayo nayiphi na enye into.
“Siwuqale lo bhubhani umfutshane kwiiswabs kunye namajelo eendaba.Kwaye ke safumana ukunqongophala kwee-reagents.Kwaye emva koko sasinqongophele iiplastiki.Kwaye emva koko saba nokunqongophala kwee-reagents kwakhona, ”utshilo uShone waseNorth Carolina.“Kufana noSuku Lweentaka.”
Ixesha lokuposa: Feb-12-2022