Ukuphathwa kolwelo oluzenzekelayoibhekisa kusetyenziso lweenkqubo ezizenzekelayo endaweni yomsebenzi wezandla ukuhambisa ulwelo phakathi kweendawo. Kwiilebhu zophando lwebhayoloji, imithamo yogqithiselo lolwelo olusemgangathweni isukela0.5 μL ukuya kwi-1 mL, nangona i-nanoliter-level transfers iyadingeka kwezinye izicelo. Iinkqubo zokuphatha ulwelo oluzenzekelayo ziyahluka ngobukhulu, ubunzima, ukusebenza, kunye neendleko.
Ukusuka kwi-Manual ukuya kwi-Automated Liquid Handling
Esona sixhobo sisisiseko yiipipette ngesandla—isixhobo esiphathwa ngesandla esifuna ungenelelo oluphinda-phindayo lwabasebenzisi kwinyathelo ngalinye (umnqweno kunye nokuhambisa). Ukusetyenziswa ixesha elide kunokukhokelela kumonzakalo woxinzelelo oluphindaphindayoi-carpal tunnel syndrome.
Iipayipi ze-elektronikimele inyathelo elilandelayo lendaleko. Zombini iipayipi ze-manual kunye ne-electronics zinokuba nemiqulu eguquguqukayo / ehleliweyo kunye neziteshi ze-1-16. Ngelixa i-pipettes ye-elektroniki ye-multi-channel yandisa i-throughput xa kuthelekiswa ne-manual ye-channel-channel pipettes, zihlala zilinganiselwe ngegalelo lomntu.Iidizayini ezizenzekelayoukoyisa oku ngokusasaza ulwelo ngaxeshanye kuwo onke amaqula emicroplate (umzekelo, iipleyiti ezingama-96 okanye ezingama-384).
Iimvavanyo zalebhu zanamhlanje zihlala zifuna "ukuhamba komsebenzi" kwamanyathelo amaninzi.Ulwelo oluzenzekelayo lweendawo zokusebenzelaDibanisa iimodyuli (umz., iishaker, izifudumezi) kunye nesoftware ukuphumeza iiprothokholi ezintsonkothileyo.
- Iinkqubo zenqanaba lokungenazihambelana nesoftware esebenziseka lula kodwa uguqulo olunyiniweyo.
- Iinkqubo ezikwinqanaba eliphezuluukuxhasa ukuphuculwa kweemodyuli, ukuhamba komsebenzi okwandisiweyo, kunye nokudityaniswa nezinye izixhobo zelebhu.
Imiba ephambili yokukhetha itekhnoloji yokuphatha ulwelo ibandakanya:
(i) Ubungakanani bomsebenzi, (ii) Ukuntsonkotha kokuhamba komsebenzi, (iii) Uhlahlo lwabiwo-mali, (iv) Isithuba seLebhu, (v) Ulawulo lobuchwephesha/ungcoliseko olunqamlezayo, (vi) Ukulandeleka, (vii) Ukuchaneka.
Ukuchaneka kwi-Automated Liquid Handling
Ukuchaneka kuxhomekeke kwiimpawu zolwelo, ubuchule bokusebenzisa imibhobho, kunye (kwinkqubo yezandla) isakhono somsebenzisi. Iimpawu zolwelo-ezichatshazelwa bubushushu, uxinzelelo, kunye nokufuma-zibandakanya:
- Viscosity(indlela yokuziphatha)
- Ukuxinana(ubunzima/umthamo weyunithi)
- Ukunamathela / ukuhambelana(ukuncamathela)
- Uxinzelelo lobuso
- Uxinzelelo lomphunga
Iisistim eziphucukileyo zilungelelanisa iiparameters ukunika ingxelo ngezi mpawu:
(i) Umnqweno/isantya sokuhambisa,
(ii) Izikhewu zomoya (ukuqhushumba/ukufuduswa komoya),
(iii) Ixesha lokuhlala kwangaphambi komnqweno,
(iv) Ingcebiso yokurhoxisa isantya.
Ubuchwephesha bokuBopha imibhobho enkulu
Ihlelwa ngokweendlela zolwelo lokuqhubela phambili:
- Ukufuduswa koMoya
- Ukufuduswa kolwelo
- Ukufuduswa okuhle
- Itekhnoloji ye-Acoustic
Evolution Timeline
I-Pipette yeManuwali (Ijelo-enye) → I-Pipette yeManuwali (Izitishi ezininzi) → I-Electronic Pipette → i-Automated Dispenser → iNqanaba lokuSebenza leNqanaba lokuNgena → iModyuli eZizimelayo zokuSebenza
| ITekhnoloji yokuBopha imibhobho | Ezona mpawu | Izicelo eziphambili |
| Ukufuduswa koMoya | Umqamelo womoya wahlula ipiston ehambayo kwisampulu | Izinzile kakhulu kwimiqulu phakathi kwe-0.5-1,000 μl |
| Ukufuduswa kolwelo | Umqamelo womoya wahlula ulwelo lwenkqubo kwisampulu | Ngokuqhelekileyo isetyenziswe ngeengcebiso ezisisigxina zensimbi engenasici; ilungele amanyathelo afuna iityhubhu ezihlatyiweyo |
| Ukufuduswa okuhle | Uqhagamshelwano oluthe ngqo phakathi kwepiston ehambayo kunye nesampuli | Ikhethwa kwi-high-viscosity kunye neesampuli eziguquguqukayo |
| Itekhnoloji ye-Acoustic | Ugqithiso lolwelo olungaqhagamshelwanga kusetyenziswa amandla eacoustic (amaza esandi) | Umthamo ophantsi kakhulu (ukuhla ukuya kuluhlu lwe-nanoliter) |
Ixesha lokuposa: May-12-2025