Automated Liquid Handlingkutanthauza kugwiritsa ntchito makina opangira makina m'malo mwa ntchito yamanja kusamutsa zakumwa pakati pa malo. M'ma laboratories ofufuza zamoyo, ma voliyumu osinthira amadzimadzi amachokera ku0.5 μL mpaka 1 ml, ngakhale kusamutsa kwa nanoliter-level kumafunika pamapulogalamu ena. Makina ogwiritsira ntchito madzi amadzimadzi amasiyana kukula, zovuta, machitidwe, ndi mtengo.
Kuchokera Pamanja kupita ku Makina Ogwiritsa Ntchito Madzi amadzimadzi
Chida chofunikira kwambiri ndipipette yamanja-chipangizo cham'manja chomwe chimafuna kuti wogwiritsa ntchito azibwerezabwereza pa sitepe iliyonse (kulakalaka ndi kugawa). Kugwiritsa ntchito nthawi yayitali kungayambitse kuvulala kobwerezabwereza ngatimatenda a carpal tunnel syndrome.
Electronic pipetteskuyimira sitepe yotsatira yachisinthiko. Ma pipette amanja ndi apakompyuta amatha kukhala ndi ma voliyumu osinthika / osasunthika ndi ma 1-16. Ngakhale kuti ma pipette amagetsi amtundu wambiri amachulukitsa mphamvu poyerekeza ndi ma pipettes amtundu umodzi, amakhalabe ochepa chifukwa cha kulowetsa kwaumunthu.Makina opangira ma dispensersgonjetsani izi pogawa nthawi imodzi yamadzimadzi m'zitsime zonse za microplate (mwachitsanzo, mbale 96- kapena 384-chitsime).
Zoyesa zamakono za labu nthawi zambiri zimafuna "mayendedwe" angapo.Makina ogwiritsira ntchito madzi amadzimadzikuphatikiza ma module (mwachitsanzo, shakers, heaters) ndi mapulogalamu kuti achite ma protocol ovuta.
- Machitidwe a msinkhu wolowerandizophatikizika ndi mapulogalamu osavuta kugwiritsa ntchito koma kusinthasintha kochepa.
- Machitidwe apamwambakuthandizira kukweza kwa ma modular, kufalikira kwa ntchito, ndikuphatikiza ndi zida zina za labu.
Zinthu zofunika kwambiri pakusankha ukadaulo wogwirizira madzi ndi:
(i) Kupititsa patsogolo, (ii) Kuvuta kwa kayendetsedwe ka ntchito, (iii) Bajeti, (iv) Malo a labu, (v) Kusamalidwa / kuwononga zowonongeka, (vi) Kutsata, (vii) Kulondola.
Precision mu Automated Liquid Handling
Kulondola kumadalira katundu wamadzimadzi, njira yopangira mapaipi, ndi (machitidwe amanja) luso la ogwiritsa ntchito. Zinthu zamadzimadzi - zomwe zimakhudzidwa ndi kutentha, kuthamanga, ndi chinyezi - zimaphatikizapo:
- Viscosity(khalidwe loyenda)
- Kuchulukana(misa / unit volume)
- Kulumikizana / kulumikizana(kumata)
- Kupanikizika pamwamba
- Kuthamanga kwa nthunzi
Machitidwe apamwamba amasintha magawo kuti aziwerengera zinthu izi:
(i) Kuthamanga / kuthamanga,
(ii) Mipata ya mpweya (kuphulika / kusamuka kwa mpweya),
(iii) Nthawi yakukhalapo kwanthawi yayitali,
(iv) Liwiro kuchotsa malangizo.
Major Pipetting Technologies
Zosankhidwa ndi njira zoyendetsera madzi:
- Kusamuka kwa Air
- Kusamuka kwa Madzi
- Kusamuka Kwabwino
- Acoustic Technology
Evolution Timeline
Pipette Pamanja (Chanelo Limodzi) → Pipette Pamanja (Chanelo Chambiri) → Pipette Yamagetsi → Wotulutsa Wokhawokha → Malo Ogwirira Ntchito → Modular Automated Workstation
| Pipetting Technology | Zofunika Kwambiri | Mapulogalamu Oyambirira |
| Kusamuka kwa Air | Mpweya wa mpweya umalekanitsa pisitoni yosuntha kuchokera ku chitsanzo | Okhazikika kwambiri pama voliyumu mkati mwa 0.5-1,000 μl |
| Kusamuka kwa Madzi | Mpweya wotsamira umalekanitsa madzi a m'dongosolo ndi chitsanzo | Amagwiritsidwa ntchito ndi nsonga zosapanga dzimbiri zosapanga dzimbiri; abwino kwa masitepe ofunikira machubu oboola |
| Kusamuka Kwabwino | Kulumikizana mwachindunji pakati pa kusuntha pisitoni ndi zitsanzo | Zokonda pazithunzithunzi zapamwamba komanso zosasinthika |
| Acoustic Technology | Kusamutsa kwamadzi osalumikizana ndi ma acoustic mphamvu (mafunde amawu) | Ma voliyumu otsika kwambiri (mpaka ku nanoliter range) |
Nthawi yotumiza: May-12-2025