At Suzhou Ace Biomedical Technology Co., Ltd., we pride ourselves on delivering high-quality, reliable laboratory and medical products that meet the stringent demands of researchers, clinicians, and healthcare professionals worldwide. As a trusted manufacturer of essentials like pipette tips, deep well plates, PCR consumables, and more, we understand that sterility is not just a feature—it’s a necessity. Contamination can compromise experiments, diagnostics, and patient safety, which is why we employ state-of-the-art sterilization methods. In this article, we delve into one of our key technologies: electron beam (e-beam) sterilization. Discover how this innovative process ensures that every product leaving our facility is impeccably sterile, safe, and ready for your critical applications.

​​What is Electron Beam Sterilization?​​

Electron beam sterilization is a cutting-edge, non-thermal sterilization technique that uses high-energy electrons to eliminate microorganisms, including bacteria, viruses, and spores. The process involves accelerating electrons to near-light speeds using an electron accelerator, creating a beam that penetrates products and packaging. When these electrons interact with microbial DNA, they cause irreversible damage by breaking molecular bonds, effectively rendering the organisms non-viable without the use of heat, chemicals, or moisture. This method is highly efficient, with sterilization cycles often completed in minutes, compared to hours for alternatives like ethylene oxide (EtO) gas. Moreover, e-beam sterilization leaves no chemical residues, making it ideal for sensitive applications in molecular biology, cell culture, and diagnostics.

​​Why We Rely on E-Beam Sterilization​​

At Ace Biomedical, we chose electron beam sterilization for its unparalleled advantages in safety, speed, and sustainability. Unlike traditional methods, e-beam processing operates at room temperature, preserving the integrity of heat-sensitive materials commonly used in our products, such as plastics for pipette tips or PCR plates. This is crucial for maintaining dimensional stability and preventing warping, which could affect performance. Additionally, e-beam sterilization is an eco-friendly option—it generates no toxic waste or greenhouse gases, aligning with our commitment to environmental responsibility. The process is also highly scalable, allowing us to sterilize large batches consistently, ensuring timely delivery without compromising quality. By avoiding chemical agents like EtO, we reduce the risk of allergic reactions or residue-related issues, providing peace of mind for end-users in sterile environments like cleanrooms or operating theaters.

​​Application to Our Product Range​​

Our diverse portfolio, including pipette tips, deep well plates, PCR tubes, and sealing films, benefits directly from e-beam sterilization. For example, our sterile pipette tips undergo rigorous e-beam treatment to eliminate contaminants that could skew experimental results in genomics or drug discovery. Similarly, PCR plates and tubes are sterilized to prevent false positives in amplification assays. The penetration depth of electrons allows for uniform sterilization even in complex geometries, such as the wells of deep well plates or the threads of screw cap tubes. We validate the process for each product type, ensuring that sterilization doses—typically ranging from 25 to 45 kGy—are optimized to achieve a sterility assurance level (SAL) of 10^-6, meaning there is less than one chance in a million of a non-sterile unit. This level of assurance is critical for applications like clinical diagnostics or biopharmaceutical production, where precision is paramount.

​​Quality Control and Assurance​​

To guarantee the efficacy of our e-beam sterilization, Ace Biomedical implements a robust quality management system compliant with international standards such as ISO 13485 for medical devices and ISO 11137 for radiation sterilization. Each batch undergoes pre-sterilization checks for bioburden levels, followed by real-time monitoring during e-beam exposure using dosimeters to verify the delivered dose. We also conduct periodic audits and biological indicator tests with resistant spores (e.g., Bacillus pumilus) to validate the process. Our facilities feature controlled environments to prevent recontamination post-sterilization, and products are packaged in sterile barriers that maintain integrity until use. By partnering with accredited irradiation centers, we ensure consistent results, backed by certificates of conformity for traceability.

​​Comparison with Other Sterilization Methods​​

While methods like gamma radiation or EtO sterilization have their merits, e-beam offers distinct benefits. Gamma radiation uses cobalt-60 sources, which can involve longer processing times and regulatory hurdles for radioactive materials. EtO, though widely used, requires aeration periods to dissipate toxic residues and poses environmental concerns. In contrast, e-beam is faster, safer, and more precise, with instant on-off capability that reduces energy consumption. For our customers, this translates to products that are not only sterile but also free from potential irritants, supporting safer workplaces and more reliable outcomes.

At Ace Biomedical, sterility is at the core of our mission to support scientific and medical advancements. Our adoption of electron beam sterilization reflects our dedication to innovation, quality, and customer trust. By leveraging this advanced technology, we ensure that every product—from routine consumables to specialized items—meets the highest standards of purity and performance. We invite you to explore our full range of e-beam-sterilized products on our website, www.ace-biomedical.com, and experience the difference that meticulous sterilization makes. For inquiries or custom solutions, contact our team—we’re here to support your success with uncompromising excellence.

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Post time: Oct-23-2025